ZFIN Image: Santos-Ledo et al., 2022, FIGURE 2

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Figure Caption

FIGURE 2

From 3 dpf onwards, OPCs cells spread throughout the visual system. At 3 dpf (a–h), olig2:EGFP/Sox2 cells are present in the INL, GCL, ONH (a, b), the optic chiasm (arrow in c), and the ventricular zones of the brain (arrow in d). Arborized olig2:EGFP cells are negative for Sox2 (arrowhead in d). sox10:tagRFP cells are present in the ONH (e, f) and the optic chiasm (e, arrow in g). Arborized olig2:EGFP/sox10:tagRFP cells are located in the POA with their projections surrounding the ON (arrowheads in g). OT also presented olig2:EGFP/sox10:tagRFP cells (arrowhead in h). At 5 dpf (i–p), olig2:EGFP/Sox2 cells are present in the INL, GCL (i, j), ON (arrow in k), and ventricular zones (arrow in l). olig2:EGFP/sox10:tagRFP cells are found in the ON with projections surrounding it (m, arrow in o), arborized olig2:EGFP/sox10:tagRFP cells are also present in the OT (arrows in p). Calretinin (CR) labels the ganglion cells and the ON. C: cartilage; D: dorsal; GCL: ganglion cell layer; H: hypothalamus; INL: inner nuclear layer; L: lateral; ON: optic nerve; ONH: optic nerve head; OT: optic tectum; POA: preoptic area; VZ: ventricular zone. Scale bar in a, e, i, m: 100 μm; in b, c, d, f, g, h, j, k, l, n, o, p: 50 μm

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Comp. Neurol.