ZFIN Image: Li et al., 2023, Figure 9

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Figure Caption

Figure 9

HSPC proliferation in genetic models with dysfunctional Cu homeostasis

(A) Expression of runx1 and cmyb in cox17 mutants (cox17^−/−) with or without Cu stresses at 33 hpf. A9, calculation of runx1 and cmyb expression in embryos from different groups.

(B) Expression of runx1 and cmyb in atp7b mutants (atp7b^−/−) with or without Cu stresses at 33 hpf. B9, calculation of runx1 and cmyb expression in embryos from different groups.

(C) Expression of foxm1 in cox17 mutants and atp7b mutants with or without Cu stresses at 33 hpf. C9, C10, calculation of foxm1 expression in embryos from different groups. A1-A8, B1-B8, C1-C8, lateral view, anterior to the left, and dorsal to the up. Data are mean ± SD. t-test, ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, NS, not significant. Scale bars, 50 μm (A1-A8, B1-B8, C1-C8).

Acknowledgments

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