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Figure 2.

ID: ZDB-IMAGE-221211-89
Source: Figures for Ikle et al., 2022

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Figure Caption

Figure 2.

SUR1 LOF [499X] abolishes K_ATP channel activity (a) Representative K_ATP channel activity in inside-out patch clamp recordings from inside-out patch clamp recordings of WT (above) and homozygous SUR1[499X] (SUR1^−/−) mutant β-cells (below) in the presence of ATP (μM), or addition of diazoxide (mM), as indicated. Voltage was clamped at −50 mV. (b) KATP channel density in WT and SUR1-/- patches (n = 17,10).

Figure Data

Phenotype details

Acknowledgments

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