ZFIN Image: Sebo et al., 2022, Figure 1

Image

Figure Caption

Figure 1

In silico identification of the putative zebrafish interleukin-1 receptor, type 1 (Il1r1). (A) Alignment of human, mouse, and zebrafish genomic regions showing conserved synteny. Shown here are the human and mouse IL-1 receptor clusters and the putative zebrafish IL-1 receptor cluster (not to scale). (B) Phylogenetic alignment of human IL1R protein sequences with putative zebrafish Il1r protein sequences. (C) Predicted protein structures of human IL1R1, zebrafish CABZ (CABZ01054965), and zebrafish ZMP (ZMP:0000000936) showing conserved domains: N-terminal signal peptide (SP), 3 extracellular immunoglobulin-like (Ig-l) domains (Ig-l 1, Ig-l 2, and Ig-l 3), a single transmembrane domain (TM), and an intracellular Toll/Interleukin-1 receptor (TIR).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol