ZFIN Image: Xu et al., 2022, Figure 6

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Figure Caption

Figure 6

Role of zebrafish Wnt signaling pathway in Cd²⁺-induced microgliosis and neuroinflammation. (A–D) Morphological alterations of microglia in 6 dpf Tg(ApoE-EGFP) zebrafish larvae, and quantification of morphological parameters. (E,F) In vivo neuroimaging and microglia counting in the optic tectum region of 6 dpf zebrafish larvae. (G) Expression patterns of genes closely related with microgliosis and neuroinflammatory response. The numerical values are presented as either mean ± SEM in histograms, or median and mean, while whiskers show 90% confidence levels in boxplots. The results of either nonparametric test or ANOVA followed by multiple comparison test are listed in Table S2. “*” indicates significant differences (* p < 0.05, ** p < 0.01, *** p < 0.001).

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Acknowledgments

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