ZFIN Image: Da'as et al., 2022, Fig. 6

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Fig. 6

The adult zebrafish mybpc3 mutant heart anatomy and histology. Adult age-matched zebrafish hearts were dissected (location: red star) and then compared across groups: (A) Control, (B) Heterozygous mybpc3+/−, and (C) Homozygous mybpc3−/− mutant. (i). Representation of the anatomical position of the heart in the adult zebrafish. (ii). The dissected heart demonstrates the two cardiac chambers, a single atrium (A), and a single ventricle (V), with an elastic, non-contractile chamber consisting of smooth muscle bulbus arteriosus (BA). (iii). Histological organization of the adult zebrafish ventricle, magnification 80×, scale bar: 10 μm. (iv). The ventricular myocardial wall is hypertrophic in the zebrafish mybpc3 mutant model (red square) when compared to the control group subset, magnification 150×, scale bar: 10 μm.

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Acknowledgments

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