ZFIN Image: Li et al., 2022, Fig. 1

Image

Figure Caption

Fig. 1

Estrogens decrease neutrophils in c-myb^hyper transgenic zebrafish.

A Flowchart for drug screening in c-myb^hyper transgenic zebrafish. For preliminary screening, 96-well plates were used and each well was placed 5 embryos to detect potential effective drugs. For secondary screening, 12-well plates were used and each well was placed more embryos (n > 15) to further verify the potential effective drugs screened from the preliminary screening. B Natural estrogens decreased SB positive cells in the CHT region in c-myb^hyper transgenic zebrafish. Many pairs of zebrafish parents were selected for the drugs treatment, the embryos from each parent pair were randomly divided into two groups, one for a compound treated group and the other for its control (DMSO group). (t-test, ***p < 0.001, **p < 0.01. n > 15.) C Progesterone had no effect on SB positive cells in the CHT region in c-myb^hyper transgenic zebrafish. (t-test, ns, no significance. n > 15).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Death Discov