ZFIN Image: Bu et al., 2021, Figure 6

Image

Figure Caption

Figure 6

Therapeutic effects of mtor inhibition on the VAC model.

(A and B) Representative Western blots showing the levels of proteins involved in mTOR signaling pathways in WT controls, vmhcl^e13/+, and vmhcl^e13/+mtor^xu015/+ mutants and quantification analysis. n = 3 biological replicates; data are presented as the mean � SD; 1-way ANOVA. (C and D) Quantification of the percent EF and FS using echocardiography in fish at 8 months. n = 12; data are presented as the mean � SD; 1-way ANOVA. (E and F) Representative images of isolated hearts and H&E staining in the apex area in fish at 8 months. (G and H) Quantification of the VSA normalized to BW and trabecular muscle density in these mutants and WT controls at 8 months. n = 6; data are presented as the mean � SD; 1-way ANOVA. Scale bars: 2 mm in E and 300 ?m in F.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ JCI Insight