Figure 4—figure supplement 1

(A) Preference index for tcf7l2 homozygous mutants and their WT siblings after addition of cadaverine (grey and on side indicated by +). Behavior was monitored prior to and after cadaverine addition for 5 min periods. Only WT adults showed a significant difference in their location 5 min afterwards compared to the min before its addition [at 6 min (p = 0.0003), 7 min (p < 0.0001), 8 min (p = 0.0067), 9 min (p = 0.0479) and 10 min (p = 0.0215), Wilcoxon signed-rank test, n = 15 adults for each group]. (B) Preference index before and after addition of cadaverine averaged over 5 min periods for WT [–0.0986 ± 0.0637 and –0.3574 ± 0.1571] and tcf7l2 adults [0.152 ± 0.0514 and 0.0361 ± 0.1015], n = 15 fish. Two-way ANOVA reveals significant effect of time [F_{(3, 152)} = 34.41, p < 0.0001], group [F_{(14, 60)} = 17.38, p < 0.0001] and interaction [F_{(42, 180)} = 5.786, p < 0.0001]. Post-hoc analysis by Bonferroni’s multiple comparisons. Dashed red lines in A and B denote midpoint of test tank.