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Figure 6
Rnf2 deficiency caused defects in the cardiac conduction system. (A) Expression of AVC myocardial markers vcana and alcama; (B) Expression of AVC endocardial and SAN marker bmp4. Red arrows indicate AVC; (C) Fluo-4 staining detects calcium signal intensity in the hearts of rnf2−/− or wild-type embryos; V, ventricle; A, Atrium; #1/#2, sample number; n = 2. (D) Quantification of fluorescence intensity in Figure 6C. *, p < 0.05; Scale bar: 0.2 mm.
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Full text @ Int. J. Mol. Sci.