ZFIN Image: Uehara et al., 2021, FIGURE 4

Image

Figure Caption

FIGURE 4

Commissural defects in nfia mutant zebrafish. Commissural axons (arrows) cross the midline in the midbrain/hindbrain boundary in wild‐type (a) (n = 4/4) and nfia heterozygous mutant (b) (n = 6/6) embryos at 3 dpf, but many of them failed to do so in nfia homozygous mutants (c) (n = 5/5). The midline crossing defects in nfia homozygous mutants were rescued by injection of NFIA^WT mRNA (d) (n = 5/5), but not by that of NFIA^K125E one (e) (n = 5/5). Axons were labeled with anti‐acetylated α‐tubulin antibody [Color figure can be viewed at wileyonlinelibrary.com]

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Am. J. Med. Genet. A