ZFIN Image: Lai et al., 2021, Figure 6

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Figure Caption

Figure 6

Increased susceptibility of LmiR21 zebrafish to diethylnitrosamine (DEN)-induced liver fibrosis and carcinogenesis. (A) Experimental design of three independent DEN treatments and doxycycline (Dox) dosing. (B) Representative images of livers with microscopic tumors identified following hematoxylin & eosin staining (indicated with arrows) one, three, and nine months after DEN treatment. Scale bar: 100 μm. (C) Representative images of livers with microscopic injuries identified by Masson’s trichome staining at one, three, and nine months after DEN treatment. Scale bar: 50 μm. (D) Representative images of livers with microscopic injuries identified by Sirius red staining at one, three, and nine months after DEN treatment. Scale bar: 50 μm.

Acknowledgments

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