ZFIN Image: Fish et al., 2021, Figure 6

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Figure Caption

Figure 6 Thrombocyte adhesion and aggregation in a hypodysfibrinogenemia model. (A) Fluorescent thrombocyte binding and adhesion in 5 dpf Tg(itga2b:EGFP) embryos after laser injury of the PCV over time in fga^+/+, fga^+/Δ19–56 and fga^{Δ19–56/Δ19–56} genotypes. Each line represents the mean (+/−SEM) of thrombocyte fluorescence reaching a threshold fluorescence within a defined area. (B) Time lapse images of fga^+/+ and fga^{Δ19–56/Δ19–56} larvae upon (0 s) and 180 s after laser injury. Fluorescence from the laser is seen at 0 s and where green fluorescent thrombocytes accumulate at 180 s. The dorsal aorta (DA), posterior cardinal vein (PCV) and site of laser injury (LI, arrows) are indicated.

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Acknowledgments

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