Image
Figure Caption

Figure 3—figure supplement 1. <italic>Myog<sup>-/-</sup></italic> mutant muscle displays unaltered <italic>igfr1a</italic> and <italic>igfr1b</italic> mRNA expression.

Schematic of adult trunk muscle processing for qPCR analysis (left). Summary of mTORC1 pathway with analysed members, positive (arrows) or negative (bars) effects are indicated (centre). Dashed lines indicate other molecules involved, plain arrow indicate direct effect, red dots represent phosphorylation. Igfr1a and igfr1b are unchanged in myog-/- muscle compared to sib (right). Symbol shapes denote paired sib and myog-/- samples, n = 5 fish/genotype, paired t-test.

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