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Figure 5—figure supplement 3.

ID: ZDB-IMAGE-200822-32
Source: Figures for Yang et al., 2020

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Figure Caption

Figure 5—figure supplement 3. Depleting myeloid leukocytes to prevent immune cell infiltration in liver leads to an increase in liver growth during an inflammatory response.

(a) Scattered dot and bar plot shows after brain-LPS injection, a relative liver size decrease in baseline and in control-p53-MO injected wild-type animals, whereas a significant increase in relative liver size in myeloid-depleted pu.1 morpholino-injected animals. Liver size was calculated based on changes in whole liver volume relative to the water-injected controls in each group. Each dot represents an individual larva analyzed. (b) Representative 3D rendered volumetric images of the whole liver from all groups and conditions analyzed. Statistical significance was determined by a two-tailed t-test for pair-wise comparison, and one-way ANOVA with Brown-Forsythe correction for the three-way comparisons. All scale bars represent 50 µm.

Acknowledgments

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