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Figure Caption
Figure 1—figure supplement 1.
Alk5-dependent pSmad3 expression.
(A) Inhibition of Tgfb receptor kinase activity suppresses pSmad3 expression. Two different Alk5 kinase inhibitors were tested. pSmad3 immunofluorescence is shown on retinal sections from uninjured fish retina. (B) Quantification of TUNEL+ cells at the site of retinal injury in heat shock-treated Wt and hsp70:ca-Alk5 fish. Scale bar is 50 microns. Error bars are SD.
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