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Fig. s5 Loss of prdm16 decreases expression of cartilage and bone markers, sox9a and runx2a, in zebrafish. (A-B) Wildtype or prdm16−/− mutant embryos were collected and in situ hybridization was performed for sox9a (A) or runx2a (B) at 48 hpf. Shown are ventral views for each transcript. Black arrow heads indicate areas of reduced expression of these transcripts in the developing cartilage and bone structures of the craniofacial skeleton. Scale bars, 250 μm. Abbreviations: eye (e).
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Reprinted from Developmental Biology, 461(2), Shull, L.C., Sen, R., Menzel, J., Goyama, S., Kurokawa, M., Artinger, K.B., The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development, 132-144, Copyright (2020) with permission from Elsevier. Full text @ Dev. Biol.