ZFIN Image: Rissone et al., 2019, Fig. 7.

Image

Figure Caption

Fig. 7.

Altered expression of oxidative stress markers in ak2^hg14 embryos. Expression analysis of oxidative stress markers in ak2^hg14 and control sibling (WT) embryos at 4 or 5 dpf. (A) Upregulated expression of several prdx genes in the otic vesicle and PLL at 4 dpf. Bottom panel for prdx1 marker: the black arrows indicate ectopic expression of the marker in PLL neuromasts of the corresponding embryos. (B) Downregulated expression of gpx4a and gpx4b markers at 4 dpf. (C) Specific downregulation of prdx2 marker at 5 dpf in PLL neuromasts and caudal hematopoietic tissue (red arrowhead, CHT). Scale bars: 200 µm. (D) Comparison of gstp1 expression in the PLL neuromasts in control embryos, ak2^hg14 null and ak2^hg16 hypomorphic mutants at 4 dpf. Two different embryos per genotype are shown. Lateral views with anterior to the left. Black arrowheads indicate the otic vesicle. Scale bars: 100 µm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.