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Fig. 5
mab21l2 −/− possess elevated cell death in their optic stalk. A‐C,E‐G: TUNEL stain of wild‐type (A‐C) and mab21l2 −/− mutant (E‐G) embryos. Compared with wild‐type, 22SS mutant embryos (E,F) possess an increase in cell death in the optic stalk region of the eye. This difference persists through 26SS (G). D,H: Pax2 and TUNEL co‐stain of 26SS wild‐type (D) and mab21l2−/−(H) embryos. Compared with wild‐type (D), mab21l2 −/−embryos possess increased dying cells in the pax2+optic stalk region. I: Quantification of the proportion of pax2+ and TUNEL+ cells in D and H. Note a significantly higher (P = 0.014) proportion of pax2+ cells are TUNEL+ in mab21l2 −/− mutants when compared with wild‐type embryos. Dorsal is up in all panels. Scale bars = 50 μm
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