ZFIN Image: Jiménez-Amilburu et al., 2019, Fig. 1

Image

Figure Caption

Fig. 1

Crb2a localization changes during cardiac trabeculation in zebrafish. (A-B″) Crb2a immunostaining in Tg(myl7:ras-EGFP)hearts at 50 (A-A″, n=12) and 74 (B-B″, n=15) hpf. At 50 hpf, Crb2a mostly localizes to the apical junctions between CMs (A-A″, arrowheads). At 74 hpf, Crb2a localizes to the entire apical membrane of compact layer CMs (B-B″, arrowheads), and is not observed in delaminated CMs (B′,B″, ø). (C-D′) Maximum intensity projections of ventricles showing junctional Crb2a immunostaining at 50 hpf (C,C′) and apical Crb2a immunostaining at 74 hpf (D,D′). (E) Schematic illustration of Crb2a relocalization in CMs from junctional to apical during the onset of trabeculation. V, ventricle.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development