ZFIN Image: Samarut et al., 2019, Fig 6

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Figure Caption

Fig 6 Hic mutants display motor coordination dysfunction.

A, Touch-evoked escape response of hitch mutants versus their siblings at 7 dpf show a dysfunction of motor coordination of hic-/- larvae. Indeed, hic-/- larvae are not able to bend their tail in a coordinated manner in order to initiate an escape swimming response (see S1 and S2 Movies for full recordings). B, Hic-/- larvae at 7 dpf show a reduction of the trunk size as well as defects of the notochord and a change in birefringence of trunk muscles. C, Measurement of the trunk size at different age shows that the reduction in trunk length starts at 3 dpf and aggravates at 7 dpf presumably due to the motor dysfunction.

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Acknowledgments

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