ZFIN Image: Carreño Gutiérrez et al., 2019, Fig. 6

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Figure Caption

Fig. 6

Altered distribution of arginine vasopressin neurons in ednraa^−/−. In situ hybridisation showing that expression of arginine vasopressin (avp) is similar in the brain of WT (a,c,e) and ednraa^−/− (b,d,f) at 6 days (a,b) and 12 days (c,d). (e,f) Reduced expression of avp in the ventral parvocellular preoptic area of ednraa^−/− of adult fish. (g,h) In situ hybridisation showing that oxytocin (oxt) expression is similar in WT and ednraa^−/− adult fish. (i,j) Anti-AVP antibody staining shows reduced labelling in the parvocellular preoptic area of ednraa^−/− (j) compared to WT (i) (arrowheads). Dorsal magnocellular neurons have a larger cell body and thicker projections. (k) Reduced levels of AVP in the brain of ednraa^−/− compared to WT. (l) Decreased whole-body cortisol levels in ednraa^−/− compared to WT. *p < 0.05, ***p < 0.001.

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Acknowledgments

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