Gene

avp

ID

ZDB-GENE-030407-2

Name

arginine vasopressin

Symbol

avp Nomenclature History

Previous Names

arginine vasotocin (1)
avpl (1)
AVT (1)
vasotocin neurophysin (1)
vsnp
VT-NP (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have neuropeptide hormone activity. Localizes to axon hillock. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Is expressed in nervous system. Orthologous to human AVP (arginine vasopressin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

39 figures from 29 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With avp Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
neurohypophyseal diabetes insipidus	Alliance	Diabetes insipidus, neurohypophyseal	125700

Associated With avp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR022423	Neurohypophysial hormone, conserved site
Family	IPR000981	Neurohypophysial hormone
Homologous_superfamily	IPR036387	Neurohypophysial hormone domain superfamily