ZFIN Image: Zhang et al., 2018, Fig. 9

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Figure Caption

Fig. 9

Mitochondrial defects in hair cells. (A) Assessment of mitochondrial function in hair cells by enzyme histochemistry (EHC) staining for SDH and COX in the frozen-sections of posterior macula of mtu1^−/−, mtu1^+/− and mtu1^+/+ zebrafish at 5dpf. Loss of EHC signal is indicated by arrows (magnification X400). V, ventral; L, lateral; Ov, otic vesicle; Hc, hair cell; Sc, supporting cell. (B) Mitochondrial networks from hair cells of inner electron microscopy. Ultrathin sections were visualized with 5000×, 10 000×, 20 000× and 60 000× magnifications. (C) Quantification of mitochondrial numbers of hair cells from the mtu1^−/−, mtu1^+/− mutant and mtu1^+/+ zebrafish. The calculations were based on 50 different hair cells of mtu1^−/−, mtu1^+/− mutant and mtu1^+/+ zebrafish, respectively. Graph details and symbols are explained in the legend to Figure 3.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.