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Fig. S7
Roles of hair bundle polarity and neuromast position in the dependence of mechanotransduction channel function on Tmc2b for neuromasts MI1 and M2. Images of hair cells from neuromasts MI1 (a,b) and M2 (c,d) of tmc2b+/- and tmc2b-/- 6-dpf larvae. FM1-43FX (red) presence reveals functional channels, and phalloidin (cyan) shows hair bundle polarity. Qualitative maps (yellow) of micrographs indicate that MI1 hair cells with ventrally facing hair bundles and M2 hair cells with dorsally facing hair bundles preferentially function (red) in tmc2b-/- mutants. Scale bar = 5 μm.
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