Fig. 4
MTHs were important in angiogenesis during zebrafish development. A comparison between control and MCT8 morphant zebrafish embryos at 25hpf is presented. (A). WISH expression analysis of flt4 showed that MTHs regulate flt4 expression in a context dependent manner. Lateral images of the head (first panel) and the trunk (second panel) are shown. The red arrowheads indicate the mid-central vein, the green arrowheads indicate the primordial hindbrain channels and the black arrowheads indicate the intersegmental vessels. CV - Cardinal vein, DA - Dorsal artery, hb – hindbrain, mb – midbrain, nt - notochord. In all the images the scale bar represents 100 μm.