Image
|
Figure Caption
Fig. S6
Knockdown of tnfa and tnfr2 causes neural defects.
(A) In Tg(ngn1:egfp) embryos injected with either tnfa or tnfr2 MOs, we observed ectopic axons that did not navigate to the DREZ. (B) Quantification of the number of ngn1+ cells per DRG at 72 hpf in wildtype, tnfa and tnfr2 morphants. (C) Quantification of sox10+ glia at 96 hpf in wildtype (n = 60 DRG). The tnfa (n = 61 DRG) and tnfr2 morphant (n = 44 DRG) larvae showing the glial ensheathment defect persists to 96 hpf. Scale bar, 25 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS Genet.