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Fig. S5
Increased apoptosis in 142C-/- embryos and upregulated expression of apoptotic genes upon knock down of miR-142a-3p.
(a) TUNEL assay displayed more apoptotic cells in the AGM region of 142C-/- embryos. The number was quantified according to the TUNEL positive cells in the AGM region (mean±SD, n=3, *P<0.05). (b) Microarray analysis revealed that apoptotic genes represented by different colors of graph bar including trim50, p53, phlda3, caspase8, xrcc5, fas, sixx-35d8.1, and ypel3 were increased in the miR-142a-3p morphants at 2 and 4 dpf.
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