ZFIN Image: Halluin et al., 2016, Fig. 2

Image

Figure Caption

Fig. 2

Pax6a but not Pax6b are required for habenular neurogenesis.

Whole-mount in situ hybridization against cxcr4b (A-D) or brn3a (E-H) showing the epithalamus of wild type (A,E), pax6b^sa86 mutant embryos (B,F), pax6a morpholino injected embryos (C,G) or pax6b^sa8;pax6a morphant embryos (D,H) at 36 (A-D) or 48 (E-H) hpf. Whereas the expression of cxcr4b and brn3a appears unaffected in pax6b^sa86 mutant embryos (B, n = 6/6 and F, n = 5/5) compared to the expression in wild type controls (A and E, n = 5/5), expression of both genes is abrogated after injection of morpholinos against pax6a in either wild type (C, n = 4/6 and G, n = 6/8) or pax6b^sa8 embryos (D and H, n = 4/4). Embryos are viewed dorsally with anterior up.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One