ZFIN Image: Gioia et al., 2017, Fig. 5

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Figure Caption

Fig. 5

4PBA treatment ameliorated the tail shape (A) and normalized the neural spine slope (B) of Chi/+ fish after 14 weeks of treatment. Scale bar: 1 mm in (A) and 500 µm in (B). (C) Transmission electron microscopy of 11 dpf Chi/+ larvae showed a general reduction of the ER cisternae size after 4PBA treatment. Magnification 12000X. (D) Representative images of picro sirius red staining Chi/+ zebrafish regrown tail after 7 days from tail clipping in absence or presence of 4PBA. A strongest signal in the sample obtained from 4PBA treated fish confirmed a higher amount of collagen in the matrix following 4PBA treatment. White lines indicate the portion of tail regrown in 7 days. Magnification 10X.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.