Image
|
Figure Caption
Fig. S6
MMP14 distribution is not altered in kif5Blof mutants.
Chondrocytes and perichondrium are positive for MMP14 in Wt (A) and kif5Blof (B). Western blot reveals no significant changes [90] in MMP14 levels (C). Scale bar: 1 μm. D-G) Wt embryos show no kif5Blof-like phenotypes when exposed to broad-spectrum metalloproteinase inhibitor (E, F) or the MMP inhibitor GM6001 (G), although some cells were extruded from the cartilage at high concentrations of EDTA (arrow in F).
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS Genet.