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Reprinted from Developmental Biology, 418(1), Lee, E.M., Yuan, T., Ballim, R.D., Nguyen, K., Kelsh, R.N., Medeiros, D.M., McCauley, D.W., Functional constraints on SoxE proteins in neural crest development: the importance of differential expression for evolution of protein activity, 166-78, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.