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Fig. 5
PmSoxE2 promotes differentiation of xanthophores in cls mutant zebrafish. (A-B) 76 hpf zebrafish embryos stained with methylene blue to detect presence of xanthophores. (A) cls mutant lacking differentiated xanthophores. (B) xanthophores in cls mutants injected with the pCS2-PmSoxE2 construct. (C) inset in “B” ; higher magnification highlights the presence of xanthophores following PmSoxE2 injection. (D) morphology of xanthophores in a wildtype 76 hpf embryo. Orientation: anterior facing left.
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Reprinted from Developmental Biology, 418(1), Lee, E.M., Yuan, T., Ballim, R.D., Nguyen, K., Kelsh, R.N., Medeiros, D.M., McCauley, D.W., Functional constraints on SoxE proteins in neural crest development: the importance of differential expression for evolution of protein activity, 166-78, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.