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Fig. S4
BMP signaling inhibition does not interfere with re-activation of aldhla2 and wt1b in the endocardium and epicardium. Related to Figure 6.
(A) Treatment of myl7:GFP transgenic fish with 5 µM Dorsomorphin for 4 days does not interfere with expression of Aldh1a2 in endocardial cells (arrow) at 7 dpi. Scale bar, 50 µm.
(B) Treatment of wt1b:GFP transgenic fish with 5 µM Dorsomorphin for 4 days does not interfere with epicardial expression of GFP (arrow) at 7 dpi. Dashed lines, wound boundary. Scale bar, 100 µm.
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Reprinted from Developmental Cell, 36(1), Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noël, E.S., Grün, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G., Bakkers, J., Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration, 36-49, Copyright (2016) with permission from Elsevier. Full text @ Dev. Cell