Fig. 8
Rescue of the Cdk9-knockdown phenotype using capped cdk9 mRNA or Larp7-Mo-SB. (A–C) Survival and phenotype score in embryos treated with CDK9-Mo-SB (Cdk9-Mo), LARP7-Mo-SB (Larp7-Mo), CDK9-Mo-SB+cdk9 mRNA, Cdk9-Mo-SB+Larp7-Mo-SB assessed independently during the first 120hpf (n=3 experiments, n>50 embryos per group). (D) Effects of rescuing the Cdk9-knockdown phenotype (cdk9 mRNA or Larp7-Mo-SB) on recovery of the cardiac function after laser injury (N=3, n=20–30 embryos per experiment). Two-way ANOVA and Bonferroni post-hoc test; ns, non-significant; *P<0.05, **P<0.01 and ***P<0.001. Means±s.e.m. are shown in B, C and D.