ZFIN Image: Heier et al., 2015, Fig. 3

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Figure Caption

Fig. 3

HS2 promotes whole genome duplication and tetraploidy. A,B: Control (A) and HS2-treated (B) embryos derived from in vitro fertilization with untreated sperm, at 5 dpf. In HS2-treated embryos, the embryonic cavity (asterisk) is distended compared with controls, and the swim bladder (arrowhead) is not inflated. C,D: Chromosome counts in cells from 24 hpf embryos. C: Normal diploid chromosomal content observed in cells from embryos exposed to normal temperatures and which exhibit no cell division stall. D: Tetraploid chromosomal content in cells from HS2-treated embryos and which showed a cell division stall in the second cell cycle.

Acknowledgments

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