ZFIN Image: Pagán et al., 2015, Fig. 1

Image

Figure Caption

Fig. 1

csf1r Mutant Zebrafish Are Hypersusceptible to M. marinum Infection

(A) Survival of adult zebrafish injected intraperitoneally with ~273 M. marinum or an equivalent volume of PBS (mock). n = 30 for each group.

(B) Bacterial burdens (CFU, colony-forming units) of adult zebrafish infected intraperitoneally with ~115 CFU of M. marinum. Horizontal lines indicate mean values.

(C) Survival of zebrafish larvae injected with PBS (mock) or ~193 M. marinum via the caudal vein. n = 30 for each group.

(D and E) Representative images (D) and mean bacterial burden (E) of larvae infected with ~200 fluorescent M. marinum via the caudal vein. Scale bar, 300 µm. Error bars indicate standard error of the mean (SEM).

Statistical significance was determined by log-rank test (A, C) or two-tailed unpaired Student’s t test (B, E). Data are representative of more than three experiments. See also Figures S1-S3 and Movies S1 and S2.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Host Microbe