Fig. 7
Co-injection of zimp7-sp MO and mRNA restores the normal level of expression of markers in embryos. (A) Anterior views of 3-somite stage embryos with dorsal toward the top. Expression of hgg1 is shown for control embryos, zimp7-sp MO injected embryos and embryos co-injected with zimp7-sp MO plus the indicated amounts of zimp7 mRNA. (B) Expression of gsc at shield stage in control embryos, zimp7-sp MO injected embryos and embryos co-injected with zimp7-sp MO plus the indicated amounts of zimp7 mRNA. Dorsal views. (C and D) For both markers the expression area was measured for a group of embryos (numbers indicated at the bottom of each bar) and the average area was plotted for each condition. Statistical analysis indicated a significant rescue of the normal level of expression for both markers. Bars represent standard deviation. **p<0.01; ***p<0.001.
Reprinted from Developmental Biology, 403(1), Moreno-Ayala, R., Schnabel, D., Salas-Vidal, E., LomelĂ, H., PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development, 89-100, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.