ZFIN Image: Kantarci et al., 2015, Fig. 10

Image

Figure Caption

Fig. 10 Bmp signaling mediates the effects of Tfap2a on SAG development.

(A-L) Cross sections (medial left, dorsal up) through the otic vesicle just posterior to the utricular macula showing expression of her4 (A-D) and deltaB (E-H) at 26 hpf and ngn1 (I-L) at 28 hpf in control embryos (A, E, I), hs:tfap2a embryos (B, F, J), DM-treated hs:tfap2a embryos (C, G, K) and DM-treated wild-type embryos (D, H, L). All specimens were treated with 1% DMSO and heat-shocked at 24 hpf. (M-P) Mean and standard deviation of the total number of deltaB or her4 expressing cells inside the otic vesicle or in the TA pool at 26 hpf under conditions indicated in the color key (counted from serial sections, n = 3–6 ears per time point). (Q-S) Mean and standard deviation of the total number of ngn1+ cells at 28 hpf (Q) and Isl1+ SAG neurons at 30 hpf (R) and 37 hpf (S) under the conditions indicated in the color key. Asterisks (*) indicate statistical differences between the groups indicated in brackets.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.