ZFIN Image: Gerlach et al., 2014, Fig. S13

Image

Figure Caption

Fig. S13 Two other independent pax2a morpholinos rescue ectopic gene expression in the pronephros of prk_CI/ζ deficient embryos. (Left column) Brightfield images show live wild-type control and prk_CI/ζ+pax2a knockdown embryos at the 72 hpf stage (lateral view, anterior to the left). (Middle column) WISH panels show wt1a or podxl (purple) in wild-type embryos and triple morphants. (Right column) Double WISH panels show wt1a or podxl (purple) and cdh17 (red) in wild-type embryos and triple morphants. Knockdown of pax2a, with either previously published MO1 or MO4, was associated with ectopic neck expression of wt1a or podxl that was exclusive of the cdh17+ tubule domain.

Acknowledgments

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Reprinted from Developmental Biology, 396(2), Gerlach, G.F., Wingert, R.A., Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta, 183-200, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.