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Fig. S3
aldh7a1 loss-of-function phenotype.
(A,D) Aldh7a1MO1 injected embryos developed bent tail compare to control MO injected embryos. (A-F) Lateral view of zebrafish eye at 50 hpf. Co-injection of Aldh7a1MO1 and Aldh7a1MO2 developed coloboma(I n=36/41,J n=25/31), compared to(G,H) control MO injected embryos.(C-F) Sagittal section of eye. Asterisks indicate edges of optic fissure, arrow indicates ventral defect in the eye at 4d.
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