ZFIN Image: Ju et al., 2014, Fig. 5

Image

Figure Caption

Fig. 5

Mdm2 expression in zOPGs. (a) In a cryosection of an eye tumor, Mdm2 was overexpressed in the sparsely nucleated glioma region, but not in the densely nucleated neural retinal tumor. (b) Immunofluorescence of a wild-type fish retina showed some overlap of Mdm2 and GFAP expression in Müller glial cells in the ONH. Insert shows close-up of staining. (c) In a transverse cryosection from a fish with asymmetric optic tectum development, the enlarged tectal lobe stained positive for Mdm2, but the contralateral lobe showed little staining. (d) Specific Mdm2 staining could be blocked by the Mdm2 immunizing peptide. OT, optic tectum.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Oncogenesis