ZFIN Image: DuVal et al., 2014, Fig. 1

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Figure Caption

Fig. 1

Zebrafish harboring homozygous mutations in gdf6 can be raised to adulthood and do not display overt skeletal defects.

A. gdf6^-/- fish are viable into adulthood, exhibit variably penetrant microphthalmia and normal body morphology. B. gdf6^-/- fish exhibit somewhat decreased survival compared to gdf6^+/+ siblings (n = 11 gdf6^-/- fish; n = 4 gdf6^+/+ siblings). C, D. gdf6^-/- fish lack overt skeletal phenotypes, as revealed by (C) clearing and staining or by (D) microCT analysis. The latter is further represented as Supplemental Movie S1. Scale bars are 5 mm. A variety of fin morphologies were present in the fish examined, but these were neither different between experimental groups (genotypes) nor a significant covariant with swim performance (see Results).

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Phenotype details

Acknowledgments

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