ZFIN Image: Rosenfeld et al., 2013, Fig. 8

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Figure Caption

Fig. 8

Hspb7 is required in Kupffer′s vesicle for normal morphogenesis. (A, B) Confocal stack and DIC images, respectively, of the KV in wildtype and morphant embryos derived from the sox17:gfp reporter strain, as indicated at the 8–10 somite stage. In this case, embryos were injected with MOs at the 1K stage, and selected for YSL-specific deposition using a reporter dye. Embryos in (A) were stained with anti-acetylated tubulin antibody (red). The bars represent 10 µm. (C–E) Quantification of KV phenotypes noting average cilia number (C), cilia length (D) or KV width (E). In each sample n was at least five embryos. The asterisk indicates p<0.05 according to Student′s t-test in comparison to the standard control group.

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Acknowledgments

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Reprinted from Developmental Biology, 381(2), Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T., Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis, 389-400, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.