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Fig. 3
Hspb12 is required for normal numbers of ventricular cardiomyocytes. (A) Representative cardiac phenotypes observed at 48 hpf development in embryos derived from the myl7:gfp; myl7:dsRed-nls reporter strain stained with S46 antibody to differentiate the atrium (blue) from the ventricle (green). (B) Quantification of cardiomyocytes in wildtype embryos (wt, n=7) or embryos injected with standard control MO (control, n=7), hspb7 MO (hspb7, n=7), hspb12 MO (hspb12, n=8), or both hspb7 and hspb12 MOs (hspb7+12, n=6). Np<0.05 by Student′s t-test in comparison to standard control group. The bars represent 10 μm.
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Reprinted from Developmental Biology, 381(2), Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T., Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis, 389-400, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.