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Fig. 5 Heart looping and regional differentiation defects in wnt11r-/- mutants.
(A) cmlc2 ISH showing the looping defect in wnt11r-/- mutants. (B) Atrio-ventricular axis angle in wild-type (left, green) and wnt11r-/- mutants (right, blue). N indicates the total number of embryos from 3 experiments. (C) Defective regional differentiation of heart in wnt11r-/- mutants, similar to those seen in tbx1-/- mutants. Scale bars: 50 μm.
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