ZFIN Image: Wolf et al., 2013, Fig. 1

Image

Figure Caption

Fig. 1 Otp regulates the expression of fezf2 and foxb1.2 in the putative mammillary area. Whole-mount in situ hybridization (WISH) to detect the expression of fezf2 and foxb1.2 in 2-dpf wild-type (A,C,E) and otpa^m866 mutant zebrafish embryos injected with 4 ng otpb morpholino (MO) (B,D,F). (A-D) In embryos lacking Otp activity, the fezf2 expression domain is strongly reduced in the PO (arrows) and expanded in the posterior part of the hypothalamus (brackets; C and D are more dorsal planes to A and B in the same embryo; n=11/11). (E,F) In embryos lacking Otp activity, foxb1.2 expression is expanded in the putative mammillary area (MA) (arrowheads; n=17/17). Dorsal views are shown. PO, preoptic area; Hyp, hypothalamus; LOF, loss-of-function. Scale bar: 100 μm.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development