ZFIN Image: Bhat et al., 2013, Fig. 5

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Fig. 5 Co-misexpressing foxi1 and gata3 in tfap2a/c morphants. A-D, Expression of pax2a in the otic/epibranchial placodes at 12 hpf. E–H, Expression of fgf24 in the otic placode at 12 hpf. I–L, Expression of dlx3b in placodal tissues at 12 hpf. M-P, otic vesicle at 24 hpf. Non-transgenic controls and hs:foxi1-hs:gata3 double transgenic embryos are marked across the top, and the lower half of each panel shows tfap2a/c morphants and double transgenic tfap2a/c morphants. Activation of the transgenes at 7 hpf partially rescued otic development in tfap2a/c morphants. Images show dorsal views with anterior to the top (A-L) or lateral views with anterior to the left (M-P).

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Acknowledgments

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Reprinted from Developmental Biology, 373(1), Bhat, N., Kwon, H.J., and Riley, B.B., A gene network that coordinates preplacodal competence and neural crest specification in zebrafish, 107-117, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.