Image
|
Figure Caption
Fig. S4 Loss of ccdc94 compromises the anti-apoptotic function of Bcl-2. Wild-type (wt, derived from crossing wild-type parents) or rs7 mutant embryos (derived from crossing rs7 heterozygous parents) were injected at the one-cell stage of development with the indicated amounts of mRNA encoding zbcl-2, zbcl-xL, or egfp as a control (cntl). Embryos were then irradiated at 24 hpf with 8 Gy IR and analyzed three hours later by immunofluorescence to detect activated Caspase-3. Mutants were genotyped as in Figure 2C–2D. Representative data from three independent experiments is shown.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS Genet.