ZFIN Image: Niu et al., 2012, Fig. 9

Image

Figure Caption

Fig. 9 Knockdown of Sec31a resulted in hypoplastic digestive organs. (A) Western blotting analysis of Sec31a and Sec13 in sec31a-ATG MO (31a-ATG MO) and standard control MO (st MO) injected embryos at 4 dpf, respectively. β-Actin was used as the loading control. (B-D) WISH using the fabp10a (B), trypsin (C) and fabp2 (D) probes to examine the development of the liver, exocrine pancreas and intestine in wildtype (WT), standard control MO (st MO), and 31a-ATG MO embryos at 4 dpf. Number of embryos displaying the showed phenotype of the total embryos examined was provided at the bottom right side of each representative embryo.

Figure Data

Phenotype details

Acknowledgments

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Reprinted from Developmental Biology, 367(2), Niu, X., Gao, C., Jan Lo, L., Luo, Y., Meng, C., Hong, J., Hong, W., and Peng, J., Sec13 safeguards the integrity of the endoplasmic reticulum and organogenesis of the digestive system in zebrafish, 197-207, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.